Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/ transcription factor) encoded by the SRY gene …

The SRY gene provides instructions for making a protein called the sex-determining region Y protein. Learn about this gene and related health conditions.

SRY (which stands for sex-determining region Y gene) is found on the Y chromosome. In the cell, it binds to other DNA and in doing so distorts it dramatically out of shape. This alters the …

Mar 30, 2025 · SRY (Sex Determining Region Y) is a Protein Coding gene. Diseases associated with SRY include 46,Xx Sex Reversal 1 and 46,Xy Sex Reversal 1. Among its related …

Dec 20, 2023 · Located on the Y chromosome, the SRY gene is primarily expressed in the cells of the developing gonads. Its expression triggers a cascade of molecular events that lead to the …

May 3, 2025 · SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a …

The human testis-determining gene Sry, a single-copy gene on the short arm of the Y chromosome, encodes a high-mobility-group (HMG) box, a DNA-bending motif conserved …

In 1990, the Y was pared down to a single gene SRY (sex-determining region of the Y; Sry in mice) thought to hold the secret of the switch between male and female development . Here …

Dec 31, 2013 · The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes, such as testes. …

Sinclair et al. (1990) identified a gene, which they named SRY (sex-determining region Y), within a 35-kb sex-determining region on the human Y chromosome that was adjacent to the …